03/04/2025
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Santos Cafe Isom is a Tex-Mex and taco restaurant located on Isom Road in San Antonio, Texas. This Mexican restaurant offers a diverse menu of classic dishes, such as chile relleno, enchiladas verdes, and pork chop plates. Santos Cafe is open Monday through Saturday from 6am-3pm and Sundays from 7am-3pm. Pre-orders for pick-up are available by calling (210)524-2370.
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Address
603 Isom Road
San Antonio, TX
78216
To get to the Tex-Mex and taco restaurant located on Isom Road in San Antonio, there are options for both public transport and driving/parking.
Public Transport:
From downtown San Antonio, take the VIA bus Route 502 towards North Star Transit Center. Get off at the stop near the intersection of Isom Road and West Avenue. Walk east on Isom Road for approximately 10 minutes until you reach the Tex-Mex and taco restaurant on your left-hand side.
Driving/Parking:
If driving from downtown San Antonio, take I-10 West towards Boerne. Exit onto West Avenue and turn right onto West Avenue. Turn left onto Isom Road and continue for approximately 0.5 miles until you reach the Tex-Mex and taco restaurant on your left-hand side.
Parking is available in a lot adjacent to the restaurant or along the side streets nearby. Please be aware of any restrictions or parking signs in the area.
Opening Hours
| Monday | 6am - 3pm |
| Tuesday | 6am - 3pm |
| Wednesday | 6am - 3pm |
| Thursday | 6am - 3pm |
| Friday | 6am - 3pm |
| Saturday | 6am - 3pm |
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What people say
Tex-mex restaurants are known for their delicious and flavorful dishes that combine the best of Mexican and Texan cuisine. Santos Cafe #2 Isom in San Antonio is a prime example of a tex-mex restaurant that delivers on taste and quality.
One thing that stands out about Santos Cafe #2 Isom is their daily specials. From the #4 Texano Plate to the Torta De Asada with Fires, there's always something new and exciting to try. And if you're in the mood for something classic, they've got you covered with fan favorites like Bean & Cheese Tacos and Mini Tacos.
But it's not just the food that makes Santos Cafe #2 Isom special - it's also their commitment to customer service. They offer pre-ordering options so you can skip the line and get your food faster, and they're open seven days a week so you can satisfy your cravings any day of the week.
Overall, if you're looking for a tex-mex restaurant that delivers on taste, quality, and customer service, look no further than Santos Cafe #2 Isom in San Antonio.