Four Brothers

Four Brothers Four Brothers is a southern American restaurant located on College Street that serves hearty and flavorful dishes with South Texas, Latin, and French influences. The menu features delectable items such as Seared Duck Breast with butternut squash puree and huckleberry jus, Ribeye with café de Paris butter and herb parmesan fries, Lamb Shank, Bone-In Pork Chop with wild mushroom brandy sauce, and various cocktails including their Strawberry Cinnamon Margarita and Hurricane during special events like Mardi Gras.

Recent social media posts

Currently accepting martinis as weekend plans 🍸✨
08/29/2026

Currently accepting martinis as weekend plans 🍸✨

08/22/2026

A friendly reminder that some of the best nights happen when you grab a seat at Four Brothers and let the evening take it from there.

08/15/2026

The confidence it takes to walk into Four Brothers and say, "We're only having one drink."

That's usually right before things escalate in the best possible way.

River Walk views, handcrafted cocktails, and our Texas Trio Dips. Need we say more?Whether you're meeting friends for ha...
07/23/2026

River Walk views, handcrafted cocktails, and our Texas Trio Dips. Need we say more?

Whether you're meeting friends for happy hour or settling in for dinner, Four Brothers is serving up the flavors of Texas one shareable bite at a time.

Happy Hour daily from 2–5 PM



Omni Hotels & Resorts | Where to eat in San Antonio, TX | Where to eat San Antonio River Walk | Texas Dining | Craft Cocktails

A perfectly stirred cocktail, bold Southern flavors, and a dining experience rooted in San Antonio tradition. Meet us on...
07/17/2026

A perfectly stirred cocktail, bold Southern flavors, and a dining experience rooted in San Antonio tradition. Meet us on the River Walk and discover your new favorite dinner ritual.

🎶Live music every Friday & Saturday at 6:30 PM adds the perfect soundtrack to your evening.

Reserve your table and savor the experience.



Omni Hotels & Resorts | Where to eat in San Antonio, TX | Where to eat San Antonio River Walk | Texas Dining | Craft Cocktails

07/01/2026

Get em while they’re hot (dogs) 🌭
We’re grilling it up this 4th of July, with a selection of festive hot dogs featuring an Eloté Dog, Classic Dog, and Frito Pie Dog.

Which one will you try? See you there on the River Walk!

The grill is hot, and the plans are set.Celebrate Father’s Day at our Courtyard Cookout at Four Brothers, where great fo...
06/19/2026

The grill is hot, and the plans are set.
Celebrate Father’s Day at our Courtyard Cookout at Four Brothers, where great food and good times come together.
🎟️ Tickets are limited — secure yours through the link in bio.

06/13/2026

POV: you choose the sound of rosé 🍷
Skip the water and sip Whispering Angel this National Rosé Day at Four Brothers.
Cheers to the better pour.

06/12/2026

You heard it too, right? 🔥
That’s the sound of the grill firing up for Father’s Day.
Join us for our Courtyard Cookout at Four Brothers—good food, great company, and an easygoing way to celebrate Dad.

🎟️ Tickets are limited — link in bio to reserve your spot.



Omni Hotels & Resorts | Where to eat in San Antonio, TX | Where to eat San Antonio River Walk | Father's Day | Cookout | Workshop

The grill is hot, and the plans are set.Celebrate Father’s Day at our Courtyard Cookout at Four Brothers, where great fo...
06/11/2026

The grill is hot, and the plans are set.
Celebrate Father’s Day at our Courtyard Cookout at Four Brothers, where great food and good times come together.
🎟️ Tickets are limited — secure yours through the link in bio.

Address

112 COLLEGE Street
San Antonio, TX
78205

To reach the Southern American restaurant on College Street in San Antonio, there are several options for transportation.

By Public Transport:
- Take the bus to the nearest stop at College Street and walk towards the restaurant.

By Car:
- From Downtown San Antonio, take I-37 S and continue onto US-281 S.
- Take exit 141B toward Hildebrand Ave and merge onto NE Interstate 410 Loop.
- Turn right onto Broadway St and continue straight.
- Turn right onto College St, and the restaurant should be on your left-hand side.

Parking:
There is limited street parking available along College Street. Alternatively, there are a few paid parking lots nearby.

Opening Hours

Monday 7am - 11am
11:30am - 10pm
Tuesday 7am - 11am
11:30am - 10pm
Wednesday 7am - 11am
11:30am - 10pm
Thursday 7am - 11am
11:30am - 10pm
Friday 7am - 11am
11:30am - 10pm
Saturday 7am - 11am
11:30am - 10pm
Sunday 7am - 11am
11:30am - 10pm

Telephone

(210) 518-1063

Alerts

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What people say

Southern American restaurants are known for their delicious and hearty cuisine, and Four Brothers on College Street in San Antonio is no exception. This restaurant offers a unique blend of Southern and South Texas flavors with Latin and French influences, making it a must-visit for foodies looking for something different.

One standout dish at Four Brothers is the Seared Duck Breast served with a butternut squash puree, huckleberry jus, swiss chard, and apple butter. The combination of flavors is simply divine. Another must-try is the 14oz Ribeye smothered in café de Paris butter and served alongside herb parmesan fries. The Bone-In Pork Chop topped with wild mushroom brandy sauce and creamy pomme purée is also a crowd favorite.

But it's not just the food that makes Four Brothers special. The atmosphere is warm and inviting, perfect for a night out with friends or a romantic dinner date. And if you're lucky enough to visit on a Friday or Saturday night from 6-9pm, you'll be treated to live music that adds to the overall experience.

Four Brothers also offers seasonal cocktails like their Strawberry Cinnamon Margarita or Ranch Water for those looking to sip on something special while enjoying their meal.

Overall, Four Brothers is an excellent choice for anyone looking to indulge in Southern American cuisine with a twist. Book your reservation today and prepare to be wowed by the flavors and ambiance of this San Antonio gem.