06/23/2026
Spicy Pineapple Margarita: where spicy meets sweet. Limited time only — get it before it's gone!
See first comment below to find a location near you!
Lupe Tortilla
- Home
- Big Springs
- Us Highway 281
- Lupe Tortilla
Lupe Tortilla is a tex-mex restaurant located on the Us Highway 281. They offer brunch, lunch, and dinner with a variety of options to choose from. Their signature Blood Orange Margaritas are a must-try but only available for a limited time. Whether you want to dine-in, pick-up curbside or have it delivered, Lupe Tortilla is the perfect spot to satisfy your cravings.
Recent social media posts
Address
21103 US Highway 281 N
San Antonio, TX
78258
From San Antonio city center, take US Highway 281 heading northbound. The restaurant is located on US Highway 281 and can be found shortly after passing the intersection with Bitters Road.
For those taking public transport, bus services run along US Highway 281 and stop near the restaurant. Alternatively, there are several taxi and ride-hailing services available in San Antonio.
If driving, there is parking available directly outside of the restaurant.
Opening Hours
| Monday | 11am - 9pm |
| Tuesday | 11am - 9pm |
| Wednesday | 11am - 9pm |
| Thursday | 11am - 9pm |
| Friday | 11am - 10pm |
| Saturday | 9am - 10pm |
| Sunday | 9am - 9pm |
Telephone
Website
Alerts
Be the first to know and let us send you an email when Lupe Tortilla posts news and promotions. Your email address will not be used for any other purpose, and you can unsubscribe at any time.
Contact The Business
Send a message to Lupe Tortilla:
Shortcuts
Share
Category
What people say
Tex-mex restaurants are known for their delicious and flavorful dishes that combine the best of Mexican and Texan cuisine. Lupe Tortilla, located on Us Highway 281 in San Antonio, is a prime example of a tex-mex restaurant that truly delivers on taste and quality.
One of the standout features of Lupe Tortilla is their commitment to using fresh ingredients in all of their dishes. From the sizzling fajitas to the tangy lime margaritas, every item on the menu is made with care and attention to detail. Whether you're dining in, picking up curbside, or getting delivery, you can always count on a delicious meal from Lupe Tortilla.
Another great thing about Lupe Tortilla is their versatility when it comes to dining options. Whether you're looking for a casual lunch or a fancy dinner, they have something for everyone. And with special events like Mother's Day brunch and Easter celebrations, there's always a reason to visit Lupe Tortilla.
Overall, if you're looking for an authentic tex-mex experience in San Antonio, look no further than Lupe Tortilla. With fresh ingredients, delicious dishes, and a welcoming atmosphere, it's no wonder why this restaurant has become a local favorite.